Justin Theroux will make his directorial debut on the romantic comedy, "Dedication." Billy Crudup, Mandy Moore, Harvey Keitel, Mia Farrow and Bob Balaban are set to star in the project by Plum Pictures.

The plot revolves around a children´s book writer (Crudup) who is forced to collaborate with a young female illustrator (Moore) when his writing partner and only friend (Keitel) dies. Farrow will play the domineering mother of Moore´s character, Balaban the book´s publisher.

Theroux developed the script with screenwriter David Bromberg. Filming is scheduled for early next year in Manhattan.

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